Papers - Uwai Koji

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  1. Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukemia cells.

    S. Kanno, K. Uwai, A. Tomizawa, T. Hiura, Y. Osanai, M. Ujibe, M. Takeshita, T. Ohtake, K. Kimura, M. Ishikawa,Basic and Clinical Pharmacology and Toxicology,vol.98,(1),(p.44 ~ 50),2006.01

  2. Octylcaffeate induced apoptosis in human leukemia U937 cells.

    M. Ujibe, S. Kanno,Y. Osanai, K. Koiwai,T. Ohtake, K. Kimura, K. Uwai, M. Takeshita, M. Ishikawa,Biological and Pharmaceutical Bulletin,vol.28,(12),(p.2338 ~ 2341),2005.12

  3. Photodegradation products of propranolol: the structures and pharmacological studies

    K. Uwai, M. Tani, Y. Ohtake, S. Abe,A. Maruko, T. Chiba, Y. Hamaya, Y. Ohkubo, M. Takeshita,Life Sciences,vol.78,(4),(p.357 ~ 365),2005.12

  4. Purification and characterization of rat liver enzyme catalyzing stereoselective reduction of acetylpyridines.

    K. Uwai, N. Konno, S. Kitamura, S. Ohta, M. Takeshita,Chirality,vol.17,(8),(p.494 ~ 500),2005.09

  5. Photostability of Naftopidil

    M. Takeshita, T. Chiba, K. Uwai, K. Hisamichi, N. Sasaki, Y. Hamaya,Japanese Journal of PharmaceuticalHealth Care and Sciences,vol.31,(6),(p.464 ~ 469),2004.06

  6. Syntheses and Receptor-Binding Study of Derivativesof the Opioid Antagonist Naltrexone

    K. Uwai, H. Uchiyama, S. Sakurada, C. Kabuto, M. Takeshita,Bioorganic and Medicinal Chemistry,vol.12,(2),(p.417 ~ 421),2004.01

  7. Synthesis and Biological Activity of Photoactivatable N-Ras-Peptides and -Proteins

    M. Volkert, K. Uwai, A. Tebbe, B. Popkirova, M. Wagner, J.Kuhlmann, H. Waldmann,Journal of the American Chemical Society,vol.125,(42),(p.12749 ~ 12758),2003.10

  8. Synthesisand Reduction of (S)-(-)-Nicotine-N'-Oxide and N,N'-Dioxides by Rat Liver S-9 Fraction

    K. Uwai, H. Sato, N. Kazakami, H. Matsuzaki, M. Takeshita,Arkivoc,vol.2003,(8),(p.211 ~ 219),2003.09

  9. Photoactivatable synthetic Ras proteins:"baits"for the identification of plasma-membrane-bound binding partners of Ras.

    J. Kuhlmann, A. Tebbe, M. Volkert, M. Wagner, K. Uwai, H. Waldmann,Angewandte Chemie International Edition,vol.41,(14),(p.2546 ~ 2550),2002.07

  10. Virol A, a toxic polyacetylenic alcohol of Cicuta virosa, inhibits the GABA-induced Cl-current in the rat hippocampal CA1 Neurons.

    K. Uwai, K. Ohashi, Y. Takaya, Y. Oshima, K. Furukawa, K. Yamagata, T. Ohmura, S. Okuyama,Brain Research,vol.889,(1-2),(p.174 ~ 180),2001.01

  11. Exploring the Structural Basis of Neurotoxicity in C17-Polyacetylenes Isolated from Water Hemlock

    K. Uwai, K. Ohashi, Y. Takaya, T. Ohta, T. Tadano, K. Kisara, K. Shibusawa, R. Sakakibara, Y. Oshima,Journal of Medicinal Chemistry,vol.43,(23),(p.4508 ~ 4515),2000.11

  12. Absolute stereochemistry of cicutoxin and related toxic polyacetylenic alcohols from Cicuta virosa

    T. Ohta, K. Uwai, R. Kikuchi, S.Nozoe, Y. Oshima, K. Sasaki, F. Yoshizaki,Tetrahedron,vol.55,(41),(p.12087 ~ 12098),1999.10

  13. New Type of Feburifugine Analogues, Bearing a Quinolizine Moiety, Show Potent Antimalarial Activity against Plasmodium Malaria Parasite

    Y. Takaya, H. Tasaka, T. Chiba, K. Uwai, M. Tanitsu, H.-S. Kim, Y. Wataya, M. Miura, M. Takeshita, Y. Oshima,Journal of Medicinal Chemistry,vol.42,(16),(p.3163 ~ 3166),1999.08

  14. Syntheses and Stereochemical Assignment of Toxic C17-Polyacetylenic Alcohols, Virols A, B, and C, Isolated from Water Hemlock (Cicuta virosa)

    K. Uwai, Y. Oshima, T. Sugihara, T. Ohta,Tetrahedron,vol.55,(31),(p.9469 ~ 9480),1999.07

  15. Enantio- and Diastereocontrolled Synthesis of Epibatidine Analogues

    K. Hiroya, K. Uwai, K Ogasawara,Chemical and Pharmaceutical Bulletin,vol.43,(5),(p.901 ~ 903),1995.05

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