Papers - Uwai Koji

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  1. New Hybrid-type Squaramide-Fused Amino Alcohol Organocatalyst for Enantioselective Domino Michael Addition/Cyclization Reaction of Oxoindolines with Cyclic 1,3-Diketones

    Madhu Chennapuram, Isiaka Alade Owolabi, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, and Hiroto Nakano,ACS OMEGA,vol.3,(9),(p.11718 ~ 11726),2018.09

  2. Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

    Yuta Tsukamoto, Sotaro Ikeda, Koji Uwai, Riho Taguchi, Kazuaki Chayama, Takemasa Sakaguchi, Ryo Narita, Wan-Ling Yao, Fumihiko Takeuchi, Yukie Otakaki, Koichi Watashi, Takaji Wakita, Hiroki Kato, Takashi Fujita ,PLOS ONE,vol.13,(5),(p.e0197664 ~ ),2018.05

  3. Structure-activity relations of rosmarinic acid derivatives for the amyloid beta aggregation inhibition and antioxidant properties

    Taguchi Riho, Hatayama Koki, Takahashi Tomohito, Hayashi Takafumi, Sato Yuki, Sato Daisuke, Ohta Kiminori, Nakano Hiroto, Seki Chigusa, Endo Yasuyuki, Tokuraku Kiyotaka, Uwai Koji,EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,vol.138,(p.1066 ~ 1075),2017.09

  4. Hybrid-Type Squaramide-Fused Amino Alcohol Organocatalysts for Enantioselective Diels–Alder Reactions of 3-Hydroxy-2-Pyridones with Maleimides

    Madhu Chennapuram, U. V. Subba Reddy, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita and Hiroto Nakano,European Journal of Organic Chemistry,vol.2017,(p.4633 ~ 4641),2017.08

  5. A Diamino Alcohol Catalyzed Enantioselective Crossed Aldol Reaction of Acetaldehyde with Isatins – A Concise Total Synthesis of Antitumor Agents

    U. V. S. Reddy, M. Chennapuram, K. Seki, C. Seki, B. Anusha, E. Kwon, Y. Okuyama, K. Uwai, M. Tokiwa, M. Takeshita, H. Nakano,European Journal of Organic Chemistry,vol.2017,(p.3874 ~ 3885),2017.07

  6. Hybrid-Type Squaramide-Fused Amino Alcohol Organocatalysts for Enantioselective Nitro-Aldol Reaction of Nitromethane with Isatins

    Chennapuram Madhu, Reddy U. V. Subba, Seki Chigusa, Okuyama Yuko, Kwon Eunsang, Uwai Koji, Tokiwa Michio, Takeshita Mitsuhiro, Nakano Hiroto,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,(12),(p.1638 ~ 1646),2017.03

  7. Simultaneous analysis of major ingredients of Gardenia fruit by HPLC-MS/TQMS method

    M Galaqin, K Uwai, M Yuguchi, T Iwasa,Mongolian J. Chem.,vol.17,(p.34 ~ 37),2016.12

  8. Simple primary β-amino alcohol catalyzed enantioselective Diels-Alder reaction of 3-hydroxy-2-pyridones

    Toshihisa Takahashi, U.V. Subba Reddy, Yoshihito Kohari, Chigusa Seki, Taniyuki Furuyama, Nagao Kobayashi, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano,Tetrahedron Letters,vol.57,(51),(p.5771 ~ 5776),2016.11

  9. 2-Azanorbornane-based amine organocatalyst for enantioselective aldol reaction of isatins with ketones

    Ayumi Ogasawara, U.V. Subba Reddy, Chigusa Seki, Yuko Okuyama, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano,Tetrahedron: Asymmetry,vol.27,(20-21),(p.1062 ~ 1068),2016.09

  10. Simple Primary Amino Amide Organocatalyst for Enantioselective Aldol Reactions of Isatins with Ketones

    Jo Kimura, Ummareddy Venkata Subba Reddy, Yoshihito Kohari, Chigusa Seki, Yasuteru Mawatari, Koji Uwai, Yuko Okuyama, Eunsang Kwon, Michio Tokiwa, Mitsuhiro Takeshita, Tatsuo Iwasa and Hiroto Nakano, European Journal of Organic Chemistry,vol.2016,(p.3748 ~ 3756),2016.07

  11. Lipase-Catalyzed Domino Michael-Aldol Reaction of 2-Methyl-1,3-Cycloalkanedione and Methyl Vinyl Ketone for the Synthesis of Bicyclic Compounds

    K. Sano, Y. Kohari, H. Nakano, C. Seki, M. Takeshita, M. Tokiwa, Y. Hirose, K. Uwai,Synthetic Communications,vol.46,(1),(p.46 ~ 54),2016.01

  12. Chiral primary amino alcohol organobase catalysts for the asymmetric Diels-Alder reactions of anthrones with maleimides

    1. J. Kumagai, T. Otsuki, U. V. Subba Reddy, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, M. Tokiwa, M. Takeshita, H. Nakano,Tetrahedron: Asymmetry,vol.26,(24),(p.1423 ~ 1439),2015.12

  13. Silyloxy Amino Alcohol Organocatalyst for Enantioselective 1,3-Dipolar Cycloaddition of Nitrones to α,β- Unsaturated Aldehydes

    A. T. Otsuki, J. Kumagai, Y. Kohari, Y. Okuyama, E. Kwon, C. Seki, K. Uwai, Y. Mawatari, N. Kobayashi, T. Iwasa, M. Tokiwa, M. Takeshita, A. Maeda, A. Hashimoto, K. Turuga, H. Nakano,Eur. J. Org. Chem.,vol.2015,(33),(p.7292 ~ 7300),2015.11

  14. Evaluation of the effects of amyloid<beta>aggregation from seaweed extracts by a microliter-scale high-throughput screening system with a quantum dot nanoprobe

    T. Ogara, T. Takahashi, H. Yasui,K. Uwai, K. Tokuraku,J. Biosci. Bioeng.,vol.120,(1),(p.45 ~ 50),2014.12

  15. Chiral Primary Amino Amide Alcohol Organocatalyst for the Asymmetric Michael Addition of 4-Hydroxycoumarin with α,β-Unsaturated Ketones

    J. Kumagai, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, H. Nakano,Heterocycles,vol.90,(2),(p.1124 ~ 1134),2014.12

  16. Biotransformation of organic compounds in vivo using larvae of beetles (Allomyrina dichotoma) as biocatalysts

    K. Uwai, Y. Okuyama, H. Nakano,, K. Furukawa, E. Hiroshima, H. Azuma, M. Watanabe, T. Matsumoto, M. Tokiwa, M. Takeshita,Biocat. Agric. Biotech,vol.3,(p.129 ~ 133),2014.09

  17. Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines with Aldehydes using beta-Amino Alcohol Organocatalyst

    Y. Kohari, Y. Okuyama, E. Kwon, T. Furuyama, N. Kobayashi, T. Otuki, J. Kumagai, C. Seki, K. Uwai, G. Dai, T. Iwasa, H. Nakano,J. Org. Chem.,vol.79,(20),(p.9500 ~ 9511),2014.09

  18. Chiral Primary Amino Amide Alcohol Organocatalyst for the Asymmetric Michael Addition of 4-Hydroxycoumarin with α,β-Unsaturated Ketones

    J. Kumagai, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, H. Nakano,Heterocycles,vol.90,(2),(p.1124 ~ 1134),2014.09

  19. A Microliter-scale High-throughput Screening System with Quantum-dot Nanoprobes for Amyloid-β aggregation Inhibitors

    Y. Ishigaki, H. Tanaka, H. Akama, T. Ogara, K. Uwai, K. Tokuraku,PLoS ONE,vol.8,(8),(p.e72992 ~ ),2013.08

  20. Development of a novel method for warfarin synthesis via lipase-catalyzed stereoselective Michael reaction

    K. Sano, S. Saito, Y. Kohari, H. Nakano, Y. Hirose, M. Tokiwa, M. Takeshita, K. Uwai,Heterocycles,vol.87,(6),(p.1269 ~ 1278),2013.05

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