Papers - Uwai Koji

41. Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines with Aldehydes using beta-Amino Alcohol Organocatalyst

    Y. Kohari, Y. Okuyama, E. Kwon, T. Furuyama, N. Kobayashi, T. Otuki, J. Kumagai, C. Seki, K. Uwai, G. Dai, T. Iwasa, H. Nakano，J. Org. Chem.，vol.79，(20)，(p.9500 ～ 9511)，2014.09

    

42. Chiral Primary Amino Amide Alcohol Organocatalyst for the Asymmetric Michael Addition of 4-Hydroxycoumarin with α,β-Unsaturated Ketones

    J. Kumagai, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, H. Nakano，Heterocycles，vol.90，(2)，(p.1124 ～ 1134)，2014.09

    

43. A Microliter-scale High-throughput Screening System with Quantum-dot Nanoprobes for Amyloid-β aggregation Inhibitors

    Y. Ishigaki, H. Tanaka, H. Akama, T. Ogara, K. Uwai, K. Tokuraku，PLoS ONE，vol.8，(8)，(p.e72992 ～ )，2013.08

    

44. Development of a novel method for warfarin synthesis via lipase-catalyzed stereoselective Michael reaction

    K. Sano, S. Saito, Y. Kohari, H. Nakano, Y. Hirose, M. Tokiwa, M. Takeshita, K. Uwai，Heterocycles，vol.87，(6)，(p.1269 ～ 1278)，2013.05

    

45. Compatibility of heparin sodium in intravenous line with nicardipine injected from a side tubevia T-shape stopcock

    T. Hayashi, K. Uwai, E. Sasaki, K. Sasaki, Y. Iwabuchi, H. Agatsuma, T. Suzuki，Jpn. J. Pharm. Health Care Sci.,，vol.38，(11)，(p.679 ～ 687)，2012.11

    

46. Chiral Primary Amino Silyl Ether Organocatalyst for the Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines with Aldehydes

    Y. Sakuta, Y. Kohari, N. D. M. R. Hutabarat, K. Uwai, E. Kwon, Y. Okuyama, C. Seki, H. Matsuyama, N. Takano, M. Tokiwa, M. Takeshita, H. Nakano*，Heterocycles，vol.86，(2)，(p.1379 ～ 1389)，2012.08

    

47. Highly Enantioselective Synthesis of Isoquinuclidine by Diels-Alder Reaction of 1,2-Dihydropyridine Utilizing Chiral Bisoxazoline-Cu(II) Complex

    N. D. M. R. Hutabarat, C. Seki, T. Shimizu, M. Hirama, Y. Kohari, H. Nakano, K. Uwai,N.Takano, E. Kwon, H. Matsuyama，Heterocycles，vol.86，(1)，(p.203 ～ 217)，2012.06

    

48. Asymmetric synthesis of isoquinuclidines by Dielse-Alder reaction of 1,2-dihydropyridine utilizing a chiral Lewis acid catalyst

    C. Seki, M. Hirama, N.D.M. R. Hutabarat, J. Takada, C. Suttibut, H. Takahashi, T. Takaguchi, Y. Kohari, H. Nakano, K. Uwai, N. Takano, M. Yasui, Y. Okuyama, M. Takeshita, H. Matsuyama，Tetrahedron，vol.68，(6)，(p.1774 ～ 1781)，2012.02

    

49. One Step Synthesis of Optically Active Diazabicyclo[3.3.0]octanones or Diazabicyclo[4.3.0]nonanones by Asymmetric Conjugate Addition of Cyclic Hydrazine

    C. Seki, M. Hirama, T. Sato, S. Takeda, Y. Kohari, K. Ishigaki, M. Ohuchi, K. Yokoi, H. Nakano, K. Uwai, N. Takano, K. Umemura, H. Matsuyama，Heterocycles，vol.85，(5)，(p.1045 ～ 1052)，2012.02

    

50. Asymmetric Synthesis of Isoquinuclidine by Diels-Alder Reaction of 1,2-Dihydropyridine and Chiral Dienophile Utilizing a Chiral Lewis Acid

    M. Hirama, C. Suttibut, N. D. M. R. Hutabarat, C. Seki, N. Sakuta, T. Tsuchiya, Y. Kohari, H. Nakano, K. Uwai, N. Takano, M. Yasui, Y.Okuyama, K. Osone, M. Takeshita, H. Matsuyama，Heterocycles，vol.84，(1)，(p.377 ～ 384)，2012.01

    

51. A highly enantioselective Diels-Alder reaction of 1,2-dihydropyridine using a simple β-amino alcohol organocatalyst for a practical synthetic methodology of oseltamivir intermediate

    C. Suttibut, Y. Kohari, K. Igarashi, H. Nakano, M. Hirama, C. Seki, H. Matsuyama, , K. Uwai, N. Takano, Y. Okuyama, K. Osone, M. Takeshita, E. Kwon，Tetrahedron Letters，vol.52，(37)，(p.4745 ～ 4748)，2011.09

    

52. ロキソプロフェンナトリウム錠後発医薬品の単回投与での臨床効果

    吉川真一，鈴木美，村田亮，吉田進，上井幸司，鈴木常義、竹下光弘，Pain Clinic，vol.31，(5)，(p.635 ～ 640)，2010.05

    

53. Evaluation of Correlation between Dissolution Rates of LoxoprofenTablets and Their Surface Morphology Observed by Scanning Electron Microscope and Atomic Force Microscope

    S. Yoshikawa, R. Murata, S. Shida, K. Uwai, T. Suzuki, S. Katsumata M. Takeshita，Chemical and Pharmaceutical Bulletin，vol.58，(1)，(p.34 ～ 37)，2010.01

    

54. Development of Clinical Application for a Nutritional Prescription Support System for Total Parenteral/Enteral Nutrition

    S. Masuda, R. Oka, K. Uwai, Y. Matsuda, T. Shiraishi, Y. Nakagawa, T. Shoji, C. Mihara, M. Takeshita, K. Ozawa，Yakugaku Zasshi，vol.129，(9)，(p.1077 ～ 1086)，2009.09

    

55. Reactivity and efficient recycling of a chiral Pd-BINAP catalyst for catalytic asymmetric Diels-Alder reaction inionic liquid

    Y. Nishiuchi, H. Nakano, Y. Araki, R Sato, R. Fujita, K. Uwai, M. Takeshita，Heterocycles，vol.77，(2)，(p.1323 ～ 1331)，2009.02

    

56. Organocatalytic activity of 4-hydroxy-prolinamide alcohol with different noncovalent coordination sites in asymmetric Michael and direct aldol reactions

    Yuko Okuyama, Hiroto Nakano, Yuki Watanabe, Mika Makabe, Mitsuhiro Takeshita, Koji Uwai, Chizuko Kabuto, Eunsang Kwon，Tetrahedron Letters，vol.50，(2)，(p.193 ～ 197)，2009.01

    

57. Trimidox-induced apoptosis is mediated through induction of p53 in NALM-6 cells.

    S. Kanno, T. Ohtake, Y. Osanai, K. Kurauchi, M. Ujibe, K. Uwai, M. Takeshita, S. Satoh, M. Ishikawa.，Journal of Pharmacological Sciences，vol.106，(3)，(p.521 ～ 524)，2008.09

    

58. Inhibitory Effect of the Alkyl Side Chain of Caffeic Acid Analogues on Lipopolysaccharide-induced Nitric Oxide Production in RAW264.7 Macrophages

    K. Uwai, Y. Osanai, T. Imaizumi, S. Kanno, M. Takeshita, M. Ishikawa，Bioorganic and Medicinal Chemistry，vol.16，(16)，(p.7795 ～ 7803)，2008.08

    

59. Inhibitory Effect of Octylcaffeateon Lipopolysaccharaide-Induced Nitric Oxide Production inMacrophages

    Y. Osanai, S. Kanno, K. Uwai, M. Takeshita, M. Ishikawa，Pharmacometrics，vol.75，(1/2)，(p.19 ～ 24)，2008.02

    

60. Electronic effects of substituon onacetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase

    K. Uwai, N. Konno, Y. Yasuta, and M. Takeshita，Bioorganic and Medicinal Chemistry，vol.16，(3)，(p.1084 ～ 1089)，2008.02