論文 - 上井　幸司

21. New Hybrid-type Squaramide-Fused Amino Alcohol Organocatalyst for Enantioselective Domino Michael Addition/Cyclization Reaction of Oxoindolines with Cyclic 1,3-Diketones

    Madhu Chennapuram, Isiaka Alade Owolabi, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, and Hiroto Nakano，ACS OMEGA，3巻，9号，(頁 11718 ～ 11726)，2018年09月

    

22. Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

    Yuta Tsukamoto, Sotaro Ikeda, Koji Uwai, Riho Taguchi, Kazuaki Chayama, Takemasa Sakaguchi, Ryo Narita, Wan-Ling Yao, Fumihiko Takeuchi, Yukie Otakaki, Koichi Watashi, Takaji Wakita, Hiroki Kato, Takashi Fujita ，PLOS ONE，13巻，5号，(頁 e0197664 ～ )，2018年05月

    

23. Structure-activity relations of rosmarinic acid derivatives for the amyloid beta aggregation inhibition and antioxidant properties

    Taguchi Riho, Hatayama Koki, Takahashi Tomohito, Hayashi Takafumi, Sato Yuki, Sato Daisuke, Ohta Kiminori, Nakano Hiroto, Seki Chigusa, Endo Yasuyuki, Tokuraku Kiyotaka, Uwai Koji，EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY，138巻，(頁 1066 ～ 1075)，2017年09月

    

24. Hybrid-Type Squaramide-Fused Amino Alcohol Organocatalysts for Enantioselective Diels–Alder Reactions of 3-Hydroxy-2-Pyridones with Maleimides

    Madhu Chennapuram, U. V. Subba Reddy, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita and Hiroto Nakano，European Journal of Organic Chemistry，2017巻，(頁 4633 ～ 4641)，2017年08月

    

25. A Diamino Alcohol Catalyzed Enantioselective Crossed Aldol Reaction of Acetaldehyde with Isatins – A Concise Total Synthesis of Antitumor Agents

    U. V. S. Reddy, M. Chennapuram, K. Seki, C. Seki, B. Anusha, E. Kwon, Y. Okuyama, K. Uwai, M. Tokiwa, M. Takeshita, H. Nakano，European Journal of Organic Chemistry，2017巻，(頁 3874 ～ 3885)，2017年07月

    

26. Hybrid-Type Squaramide-Fused Amino Alcohol Organocatalysts for Enantioselective Nitro-Aldol Reaction of Nitromethane with Isatins

    Chennapuram Madhu, Reddy U. V. Subba, Seki Chigusa, Okuyama Yuko, Kwon Eunsang, Uwai Koji, Tokiwa Michio, Takeshita Mitsuhiro, Nakano Hiroto，EUROPEAN JOURNAL OF ORGANIC CHEMISTRY，12号，(頁 1638 ～ 1646)，2017年03月

    

27. Simultaneous analysis of major ingredients of Gardenia fruit by HPLC-MS/TQMS method

    M Galaqin, K Uwai, M Yuguchi, T Iwasa，Mongolian J. Chem.，17巻，(頁 34 ～ 37)，2016年12月

    

28. Simple primary β-amino alcohol catalyzed enantioselective Diels-Alder reaction of 3-hydroxy-2-pyridones

    Toshihisa Takahashi, U.V. Subba Reddy, Yoshihito Kohari, Chigusa Seki, Taniyuki Furuyama, Nagao Kobayashi, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano，Tetrahedron Letters，57巻，51号，(頁 5771 ～ 5776)，2016年11月

    

29. 2-Azanorbornane-based amine organocatalyst for enantioselective aldol reaction of isatins with ketones

    Ayumi Ogasawara, U.V. Subba Reddy, Chigusa Seki, Yuko Okuyama, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano，Tetrahedron: Asymmetry，27巻，20-21号，(頁 1062 ～ 1068)，2016年09月

    

30. Simple Primary Amino Amide Organocatalyst for Enantioselective Aldol Reactions of Isatins with Ketones

    Jo Kimura, Ummareddy Venkata Subba Reddy, Yoshihito Kohari, Chigusa Seki, Yasuteru Mawatari, Koji Uwai, Yuko Okuyama, Eunsang Kwon, Michio Tokiwa, Mitsuhiro Takeshita, Tatsuo Iwasa and Hiroto Nakano， European Journal of Organic Chemistry，2016巻，(頁 3748 ～ 3756)，2016年07月

    

31. Lipase-Catalyzed Domino Michael-Aldol Reaction of 2-Methyl-1,3-Cycloalkanedione and Methyl Vinyl Ketone for the Synthesis of Bicyclic Compounds

    K. Sano, Y. Kohari, H. Nakano, C. Seki, M. Takeshita, M. Tokiwa, Y. Hirose, K. Uwai，Synthetic Communications，46巻，1号，(頁 46 ～ 54)，2016年01月

    

32. Chiral primary amino alcohol organobase catalysts for the asymmetric Diels-Alder reactionsof anthrones with maleimides

    1. J. Kumagai, T. Otsuki, U. V. Subba Reddy, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, M. Tokiwa, M. Takeshita, H. Nakano，Tetrahedron: Asymmetry，26巻，24号，(頁 1423 ～ 1439)，2015年12月

    

33. Silyloxy Amino Alcohol Organocatalyst for Enantioselective 1,3-Dipolar Cycloaddition of Nitrones to α,β- Unsaturated Aldehydes

    A. T. Otsuki, J. Kumagai, Y. Kohari, Y. Okuyama, E. Kwon, C. Seki, K. Uwai, Y. Mawatari, N. Kobayashi, T. Iwasa, M. Tokiwa, M. Takeshita, A. Maeda, A. Hashimoto, K. Turuga, H. Nakano，Eur. J. Org. Chem.，2015巻，33号，(頁 7292 ～ 7300)，2015年11月

    

34. Evaluation of the effects of amyloid<beta>aggregation from seaweed extracts by a microliter-scale high-throughput screening system with a quantum dot nanoprobe

    T. Ogara, T. Takahashi, H. Yasui,K. Uwai, K. Tokuraku，J. Biosci. Bioeng.，120巻，1号，(頁 45 ～ 50)，2014年12月

    

35. Chiral Primary Amino Amide Alcohol Organocatalyst for the Asymmetric Michael Addition of 4-Hydroxycoumarinwith α,β-Unsaturated Ketones

    J. Kumagai, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, H. Nakano，Heterocycles，90巻，2号，(頁 1124 ～ 1134)，2014年12月

    

36. Biotransformation of organic compounds in vivo using larvae of beetles (Allomyrina dichotoma) as biocatalysts

    K. Uwai, Y. Okuyama, H. Nakano,, K. Furukawa, E. Hiroshima, H. Azuma, M. Watanabe, T. Matsumoto, M. Tokiwa, M. Takeshita，Biocat. Agric. Biotech，3巻，(頁 129 ～ 133)，2014年09月

    

37. Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines with Aldehydes using beta-Amino Alcohol Organocatalyst

    Y. Kohari, Y. Okuyama, E. Kwon, T. Furuyama, N. Kobayashi, T. Otuki, J. Kumagai, C. Seki, K. Uwai, G. Dai, T. Iwasa, H. Nakano，J. Org. Chem.，79巻，20号，(頁 9500 ～ 9511)，2014年09月

    

38. Chiral Primary Amino Amide Alcohol Organocatalyst for the Asymmetric Michael Addition of 4-Hydroxycoumarin with α,β-Unsaturated Ketones

    J. Kumagai, Y. Kohari, C. Seki, K. Uwai, Y. Okuyama, E. Kwon, H. Nakano，Heterocycles，90巻，2号，(頁 1124 ～ 1134)，2014年09月

    

39. A Microliter-scale High-throughput Screening System with Quantum-dot Nanoprobes for Amyloid-β aggregation Inhibitors

    Y. Ishigaki, H. Tanaka, H. Akama, T. Ogara, K. Uwai, K. Tokuraku，PLoS ONE，8巻，8号，(頁 e72992 ～ )，2013年08月

    

40. Development of a novel method for warfarin synthesis via lipase-catalyzed stereoselective Michael reaction

    K. Sano, S. Saito, Y. Kohari, H. Nakano, Y. Hirose, M. Tokiwa, M. Takeshita, K. Uwai，Heterocycles，87巻，6号，(頁 1269 ～ 1278)，2013年05月