Personnel Information

写真a

Nakano Hiroto


Affiliation centers1, etc

The Center for Creative Collaboration

The master's program in charge

Division of Sustainable and Environmental Engineering

The doctoral program in charge

Division of Engineering

The department in charge

Department of Sciences and Informatics

Job title

Professor

E-mail Address

E-mail address

Research field 【 display / non-display

  • Synthetic chemistry

Keywords for Research Field 【 display / non-display

  • 創薬

  • 有機分子触媒

Graduate school・Graduate course, etc. 【 display / non-display

  • Tohoku Pharmaceutical University

    1989.03,Doctoral program,Graduate School, Division of Pharmaceutical Sciences,Devision of Pharmaceutical Sciences,Completed,Japan

Graduate school・major, etc. 【 display / non-display

  • Tohoku Pharmaceutical University

    1983.03,Faculty of Pharmaceutical Science,Tohoku Pharmaceutical University,Graduate,Japan

Degree 【 display / non-display

  • Doctor of Pharmaceutical Sciences

Career 【 display / non-display

  • 米国コロラド州立大学化学科 博士研究員

    1997.04.01 ~ 1999.03.31

Academic Society 【 display / non-display

  • 日本化学会,日本薬学会,有機合成化学会,アメリカ化学会

Academic prize 【 display / non-display

  • 日本薬学会東北支部奨励賞

    1999.12,日本薬学会

  • 19th Malaysian International Chemistry Congress(19MICC) and International Congress on Pure & Applied Chemistry (ICPAC) Langkawi 2018, Lecture Award

    2018.10.30,MALAYSIA Chemistry Society

 

創薬を指向した新しい有機合成法の開発

Purpose of Research

新しい触媒的不斉合成法の開発と創薬シーズの探索

Summary of Research

独自に開発した触媒的不斉合成法を鍵反応とする創薬シーズ化合物の合成
Research Content

Features / Benefits of Research

1.Point of research 2.Research of novelty
  • 創薬シーズ
  • 環境調和型の安価な有機分子触媒を用いる医薬品候補化合物の効率的合成法を開発する
3.Primacy of Technology 4.Situation of patent-related
  • “新規アミノアルコール誘導体塩,アミノアルコール誘導体塩構造を有する不斉有機分子触媒及び該不斉有機分子触媒を用いた光学活性化合物の製造方法" 權 垠相,竹下光弘,中野博人, 松山春男, 特開:2011-068587
 

Books 【 display / non-display

  • パートナー医薬品化学(改訂第3版)

    佐野武弘,斉藤俊昭,堀口よし江,中野博人,宮田興子,内藤猛章,前崎直容,山内昌茂,北川幸己,西出喜代治,南江堂,一般的性質と反応,(p.321),2017.02,978-4-524-40338-7

  • パートナー医薬品化学(改訂第2版)

    佐野武弘,斉藤俊昭,堀口よし江,中野博人,宮田興子,内藤猛章,前崎直容,山内昌茂,北川幸己,西出喜代治,南江堂,一般的性質と反応,(p.295),2012.02

  • パートナー医薬品化学

    佐野武弘,斉藤俊昭,堀口よし江,中野博人,宮田興子,内藤猛章,前崎直容,山内昌茂,北川幸己,西出喜代治,南江堂,一般的性質と反応,(p.292),2008.04

Papers 【 display / non-display

  • Amino Amide Organocatalysts for Asymmetric Michael Addition of β-Keto Esters with β-Nitroolefins

    Isiaka A. Owolabi, Madhu Chennapuram, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano,Bulletin of the Chemical Society of Japan,vol.92,(3),(p.696 ~ 701),2019.01

  • Antiviral Activities of Hibiscus sabdariffa L. Tea Extract Against Human Influenza A Virus Rely Largely on Acidic pH but Partially on a Low-pH-Independent Mechanism

    Yohei Takeda, Yuko Okuyama, Hiroto Nakano, Yasunori Yaoita, Koich Machida, Haruko Ogawa & Kunitoshi Imai,Food and Environmental Virology,vol.12,(p.9 ~ 19),2019

  • 2Azanorbornane Based Amino Alcohol Organocatalysts for Asymmetric Michael Reaction of βKeto Esters with Nitroolefins

    Rei Togashi, Madhu Chennapuram, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano,European Journal of Organic Chemistry ,(24),(p.3882 ~ 3889),2019

  • Sugar Based γ-Amino Alcohol Organocatalyst for Asymmetric Michael Addition of β-Keto Esters with Nitroolefins

    Divakar Ganesan, Madhu Chennapuram, Zubeda Begum, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Suguru Tokiwa, Mitsuhiro Takeshita, and Hiroto Nakano,Heterocycles,vol.98,(11),(p.1536 ~ 1545),2019

  • A new type of amino amide organocatalyzed enantioselective crossed aldol reaction of ketones with aromatic aldehydes

    Isiaka A. Owolabi, U.V. Subba Reddy, Madhu Chennapuram, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano,Tetrahedron,vol.76,(36),(p.4705 ~ 4711),2018.09

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Editorial and Commentary 【 display / non-display

  • アミノアルコールおよびその関連化合物を有機分子触媒として用いた不斉付加環化反応の開発

    中野博人,熊谷 淳,U. V. Subba Reddy,関 千草,奥山祐子,權 垠相,2016

  • アミノ酸関連有機化合物の触媒作用を利用した高光学純度タミフル合成 中間体の新しい合成法

    中野博人,權 垠相, 奥山祐子,ファインケミカル,vol.41,(p.45 ~ 54),2012.06

  • Creations of chiral oxazolidine-type catalysts and its applications to asymmetric addition reactions

    中野 博人,奥山祐子,竹下光弘,權 垠相,小針 良仁,松山 春男,Journal of synthetic organic chemistry,2012.02

  • New Synthetic methodology for a high optical purity Tamiflu synthetic intermediate

    中野博人,Chemical industry,2011.12

  • Creations of Chiral Ligands Having Acetal Structures and Its Applications to Pd-catalyzed Reactions

    中野博人,奥山祐子,高橋康一,藤田禮子,甲 千寿子,Journal of Synthetic Organic Chemistry,vol.65,(12),(p.1191 ~ 1202),2007

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Presentaion at conference, meeting, etc. 【 display / non-display

  • Simple Primary β-Amino Alcohol Organocatalyst for Asymmetric Hetero Diels-Alder Reaction of Isatins with Enones

    Hiroto Nakano,The 14th International Conference on Cutting-Edge Organic Chemistry in Asia,The 14th International Conference on Cutting-Edge Organic Chemistry in Asia,(p.7-7),2019.09.26,北海道,日本

  • Simple Amino Alcohol and Amino Amide Organocatalysts for Asymmetric Synthesis

    Hiroto Nakano,International Congress on Pure & Applied Chemistry (ICPAC) Yangon 2019,International Congress on Pure & Applied Chemistry (ICPAC) Yangon 2019,2019.08.06,ヤンゴン,ミャンマー

  • Simple amino alcohol and amino amide organocatalysts for asymmetric reactions

    Hiroto Nakano,22nd International Conference on Past and Present Research Systems on Green Chemistry,22nd International Conference on Past and Present Research Systems on Green Chemistry,2019.04.26,バンクーバー,カナダ

  • 2-Azanorbornane-Based Amino Alcohol And Amino Amide Organocatalysts for Asymmetric Michael Reaction

    Rei Togashi and Hiroto Nakano,Chemistry Conference for Young Scientists,ベルギー化学会,他,Chemistry Conference for Young Scientists,2020.02.19,ブランケンベルヘ,ベルギー

  • 難治性掻痒に有効な新規低分子ペプチドの創成

    石田宗一郎,櫻田忍,溝口広一,関千草,上井幸司,中野博人,第37回メディシナルケミストリーシンポジウム2019,日本薬学会,第37回メディシナルケミストリーシンポジウム2019,(p.46-46),2019.11.27,八王子,日本

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Patent and utility model acquisition 【 display / non-display

  • 消毒剤

    日本,特願2015-047017,特開2016-166150,特許第6633831号

  • DISINFECTANT

    中国,201680014300.2,CN107708423A

  • 新規有機ゲルマニウム化合物及びこれを含む鎮痛剤

    日本,特願2017-242584,特開2019-108297

  • 土木工事排出濁水処理用凝集剤

    日本,特願2016-55853,特開2017-170279

  • DISINFECTANT

    ベトナム,1-2017-04016

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Class subject in charge 【 display / non-display

  • 応用化学プレゼンテーション技法バイオシステムプレゼンテーション技法

    2019,Department

  • 有機化学A

    2019,Department

  • 有機合成化学

    2019,Department

  • 有機化学C

    2019,Department

  • 有機合成化学特論

    2019,Master's program

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Education book 【 display / non-display

  • パートナー医薬品化学 改訂第3版

    2017.03

  • パートナー医薬品化学

    2008,佐野武弘,斉藤俊昭,堀口よし江,中野博人,宮田興子,内藤猛章,前崎直容,山内昌茂,北川幸己,西出喜代治,一般的性質と反応, (p.292),南江堂